To be frank, if you are holding it with one hand and reading for 8-10 hours a tablet is the wrong tool. You need a Kindle. I spend hours reading mine, but I don't hold it with one hand that whole time.
I tried the Kindle and Nook (tablet versions as I need the backlight on night flights). I prefer an all in one device and their OS wasn't cutting it. I haven't been reading for that time period lately but I'm heading out to China again and will be reading for a 13-15 hour flight.