I'm pretty sure that if you have a reference card, there shouldn't be issues but if you had to do some ROM editing / hacking to get your card to work initially, then you may have issues that require the help of netkas / Rominator (on netkas's forums) or Cindori.
Exactly. Any 4870 which looks like below (notice AMD logo on PCB, not all red PCB are reference):

will be immune to all updates (present and future).
Reference cards (or very close to) flashed with untouched OEM Apple ROM are safe.