Medical firm Johnson & Johnson (J&J) is suing the American Red Cross, alleging the charity has misused the famous red cross symbol for commercial purposes.
The charity described the lawsuit as "obscene".
It said many of the products at issue were health and safety kits and that profits from their sale had been used to support disaster-relief campaigns.
The lawsuit asks for sales of disputed products - also including medical gloves, nail clippers, combs and toothbrushes - to be stopped and unsold items to be handed over to J&J.
The firm is also seeking damages equivalent to the value of such goods sold in supermarkets such as Wal-Mart and Target.
The red cross symbol was adopted by the forerunners to the International Committee of the Red Cross in 1863.
American Red Cross was founded in 1881 but did not receive a charter from the US Congress until 1900.
J&J... first used the symbol as a trademark in 1887, the same year it was incorporated as a business.
"Our outside lawyers have looked at this and think we are on sound ground," said Mark Everson, the charity's chief executive.