The only change between the monitor working and not working is the Mac attached to it? (No different breakout/dongles, cables)
I doubt you haven’t tried this but I’d be remiss if I didn’t ask: have you tried switching which Thunderbolt plug you use on the Mac mini? E.g. It works with neither of the relevant connections on the back of the mini (there could be a plug fault, which is why I would try both)