Another regionalism is the pronunciation of the word "route." It irks me when people say "root." I finished undergrad at FSU in Tallahassee and one of my friends (a Tally native) would always think I was so quaint because I pronounced "route" as "rouwt" and "root" as something similar to "rouht". He would insist that the proper way to say "route" was "root" and the proper way to say "root" was "roooot." He also accused me of confusing "root" and "rut." The way I say "root" and "rut" are not even close to being the same, but he couldn't differentiate between the two. I think we were actually both right, as we grew up in different regions. I have a Midwestern (Iowa) accent, and when traveling abroad I am often thought to be Canadian, wheras he grew up in Tallahassee, which is very close to the southern border of Georgia.
According to the dictionary, "root" has two possible pronunciations, one was his way, the other was mine (ro?t; ro?t).