I did a restore through iTunes and set up the phone with 5.0.1 as new phone. I transferred my apps back to my phone from iTunes. I was having worse drain than with 5.0. I always have "send data to Apple" or whatever that setting is, turned off. Also turn off location services unless I need it along with bluetooth. I also leave cellular data on.
Some people mention this next step and many overlook it, but it made a world of difference for ME. Let the battery go / drain until the phone shuts off (just play Asphalt 6, that will drain the sucker) and then charge it back to 100%. I was charged to 100% at 4:00 PM Monday. I turn the phone off at night and have used it just for typical calls and emails and texts since then (phone stays on from about 8:30 AM through 11:30 PM). It is 1:45 PM Wednesday now and I have 40% battery left. It wasn't like this for me before. Highly recommend calibrating the battery. You don't need to do it very often.
Some people mention this next step and many overlook it, but it made a world of difference for ME. Let the battery go / drain until the phone shuts off (just play Asphalt 6, that will drain the sucker) and then charge it back to 100%. I was charged to 100% at 4:00 PM Monday. I turn the phone off at night and have used it just for typical calls and emails and texts since then (phone stays on from about 8:30 AM through 11:30 PM). It is 1:45 PM Wednesday now and I have 40% battery left. It wasn't like this for me before. Highly recommend calibrating the battery. You don't need to do it very often.