Just received the 1880ix-16 RAID card as an upgrade to the 1221x. When I installed it in PCI-e slot 2 (next to graphics card) and hit the power button the computer made a buzzing sound through the internal speaker and would not POST. Tried the other 2 slots same issue. Double checked card was well seated. Stuck it in one of my PC's and it booted fine. Have sent a message to Areca support. Seems like an incompatibility with new mac pro, as card is not DOA. It is a new product so maybe not tested with 2010 MP. Anybody using this series of RAID card in MP?