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Heads up, this has become a well known and widespread issue with Safari 7 in 10.9. Apple has yet to address the matter, developers haven't heard a word on it from Apple.

Many have 10.8 installed on the same system as 10.9 with the same plugin's, created new user accounts, 10.9 consistently lists numerous QTKitServer Safari Web Content Not Responding lines. Interestingly they're almost always listed under the user account, not root, meaning it's something isolated in the ~/Library/ folder but what? All things being equal aside from the different OS after a clean install, means ~99% certainty it's OS X related.
 
I got rid of the problem by deleting the Safari caches in /Library & ~/library and Safari prefs. Something was probably triggering a process that accessed QTKitServer, which helps to run older video stuff. I am told there is an issue with 32bit processes, sand boxing & QTKitServer. But although annoying the problem shouldn't crash, hang or otherwise bother safari.

EDIT: and of course having said that, it now returns.... But again, I've been assured by a developer that it's just an old process being shut out and hence it won't effect anything, and it seems not to.
 
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I have cleared cache and prefs. QTserver does not respond and certain websites hang and won't load because of it. I really wanted to try and use apple's apps this year. I guess that's not going to happen now. :(
 
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