I foresee a new class of publishing company. Imagine 5 editors leaving a big company. They hire a secretary/HR person, a marketing person, a sales person, and an IT/web guy, and setting up an 8 person office that edits and publishes e-books.
You'd have the same editing quality coming from these guys but with a LOT lower overhead for them to cover in terms of company costs. They could charge a lot less for the same quality e-book production.
As an author you wouldn't get the same marketing or the printed books, but let's say all the major publishers turned you down because your book would be too big of a risk for them. But say you're a popular blogger and you know you'll sell to your readers so you pay for this service yourself.
There are ways you can pay for a small run of printed books now...this will be similar, but I predict it will be far more poplular. I bet a TON of successful bloggers will end up writing e-books they only intend to sell to their readers. A publishing house won't be interested, but they could afford to hire a company like this and make just enough money to pay them back. So the book isn't a profit, but it brings more attention to their blog, where they actually make money.
Obviously this won't replace normal book publishers, but I think it will be a whole new market for writers who, today, just get rejection letters and leave it at that.