Is this in a browser window? You could try command-p to print then select save as PDF at the bottom left.
Thanks for the suggestion, but that does not capture the entire content of the scrolling frame.
I realize they (Prima Game Guides) want to protect their content, I suppose to prevent piracy, so they are very tricky with how they've displayed this online. Subsequently, it's hard to turn the entire thing into a pdf for off line reference, I'm not a pirate, just want this to be convenient.
This is a very big Fallout 4 guide. If I could turn each complete frame into pdf, in one shot, that would work, but would still be a lot of work. If I copy a small section, I can paste that intact to a word processor. If I try to copy an entire frame, upon paste, it turns the content into a column of single letters. Having to take screen shots of the visible portion, each frame would be composed of about 5 screen shots and there are close to 500 pages. If turned into a .pdf, I don't know if this would function as a pdf or like an image. If an image, it might destroy any search capability.
It looks like I'll be doing what Dave suggests below for the stuff I want for quick reference (by copy/paste small areas), but it will not help for doing searches. I also have a hard copy of the guide (that I purchased), but that can be a bear to search through, hence the advantage of a pdf.
Screenshot the top bit, scroll it down, screenshot the next bit and so on. Then put it together in something like Pages. I produce A3, A2, A1 size maps this way.
Thanks for the suggestion! I've used this method before. See above.