Any chance you can try 8 GB in a MacBook (Santa Rosa)?I put dual 4GB modules in an "early 2008" MacBook Pro. It saw all 8 GB according to Activity Monitor but it ran really slow -- like it was confused -- especially when I ran Compressor with 2 instances or After Effects in Multiprocessing mode (which spawns two sub-process that use 3GB each).
I went back to dual 2GB modules and it ran at normal speed again.
I'll be trying it again with the "late 2008" MacBook Pro. One of the memory makers is sending me samples. I'll report back.
6 GB seems to be a working configuration in the MacBook Pro but not 8 GB.