Assume that you have the HIV virus in your bloodstream and also assume that you are totally immune to this virus and you will never suffer from AIDS. So if you have the habit to change your partners often, you would still need to use condoms because your partner is not immune to HIV.
Same is with your data payloads that you get via the internet, email, etc. Your Mac is immune to it, but if you forward it or share it Windows PCs and servers , Android Mobiles, etc, will get infected - because of you. An AV product on your Mac stops the spreading of computer diseases. Use a condom / antivirus to protect others!
Regarding Antivirus program detection:
Most Enterprise and Education networks have sophisticated NW admission mechanisms. When you connect to the WLAN, then these systems will query the device whether an Antivirus program is installed. These systems are querying for the existence of up to 40 different antivirus programs. If present, the AV will respond positive. It is also queried whether the AV threat database is up-to-date. If the AV is not present on the connecting device is outdated, then this client is moved to a quarantined Virtual LAN where you only have limited connectivity and cannot access any Enterprise or Education computing resources.
I am using the free
Sophos Anti-Virus for Mac Home Edition on all my Macs and I hardly notice that it is there unless it disinfects an infected email attachment.
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Read the 2nd post of this thread. Sophos is not recommended.
That is pure FUD. Never experienced problems with Sophos on Lion or Mountain Lion.
By the way:
When I do a manual full system scan on my MBA 2012 11" i5 running OS X 10.8.2 with Sophos Anti-Virus for Mac Home Edition Version Version 8.0.6C then I get a CPU load of 2.1% - 3.5% for the Sophos process.
You can hardly call this a resource hog.
When it is just running in the background then it is hardly noticeable