Resolved System Preferences not responding

[JeafGilbert]

You need to unhide library folder first -> because it is a folder hidden by Apple, it is flagged, so open the Terminal and command would be:

chflags nohidden /Users/<Username>/Library

after that you will see Library folder and inside /Users/<Username>/Library/Preferences you can find com.apple.desktop.plist and remove it!

I also had the same problem. System Preferences loading taking ages and this solution worked for me:
- Open Finder
- Go > Go to Folder
- Type ~/library/preferences, click Go.
- Removed com.apple.desktop.plist
- No need to restart. Reopen System Preferences, and it worked like a charm!

Thanks!!

 

[sikane]

Fixed the Issue for Me

I ran safe boot:
http://support.apple.com/kb/ht1564