I have just had this, also noticed this dosnt only affect it at night
yesterday at home I noticed my phone wasnt receiving any emails, just got the spining wheel, tried it a few times in afternoon and evening but nothing (did do a force quite by holding the button down for a few secs till it closed)
Never thought any more of it as I was at my mac, looked at my phone this morning, 1 day 1 h standby and 22 h usage, battery was at the 10% warning, restarted phone and it came back to normal
No difference in usage yesterday (perhaps a bit less than normal) and I usually have about 50% battery at this time.
My opinion on what happened is that it knew there was mail to be received and it just constantly kept on trying, could never receive it so usage just went up and up
for info I have
MobilMe - Push
Exchange - Push
Personnal - Fetch
Gmail - Fetch