Become a MacRumors Supporter for $50/year with no ads, ability to filter front page stories, and private forums.
Mine sits at the bottom of my apple 30" cinema display as small as it can be with no magnification. The only thing in the dock is Finder and Trash. I use quicksilver and keyshortcuts. Most of the time my wireless mouse is turned off.
 
Register on MacRumors! This sidebar will go away, and you'll see fewer ads.