So I think that I will get a nMP for scientific computing. I do have access to clusters, but it is nice to have something fully controlled (And where I have priority) and where I have exactly the same environment as my development. I use GPUs pretty heavily. It is a lot easier for me to get a base model. But I could consider something else if I make the purchase in October. Also, it has been out a while. When is the next version available for purchase? For scientific computing, how much of an advantage is the 6C base model? Are the 500s really better than the 300s for OpenCL work?