I shut my Mac down and disconnect the power every night before I go to bed.
Don't know if that is right or wrong, but it saves electricity and noise pollution in my house.
I have been doing this for 3 years now and have not had any trouble.
It is the right way to do it. Unfortunately I guess most of us can't do without the instant gratification factor of tweaking the mouse and having it be usable a few seconds later.