I tried the dev version of Google Chrome and I really like it. It opens on one bounce (sometimes even less), which is about the same as my Safari, so I'd give them a tie on this aspect.
Interface - I find Chrome's interface neat and perhaps even nicer than Safari's. I don't mind the tabs on top, BUT having them on top will prevent you from seeing the "title" of the website you are browsing. I don't know, perhaps I would get used to it eventually, but I like it when there is a name of whatever topic/site I'm browsing on top of the browser.
In Chrome, you gain more viewing space without the Status Bar below (yes, I know you can hide it in Safari too, but then you won't ever see what link you're about to click etc.) - kudos to Chrome on this one for popping up a little status bar info in the lower left corner whenever the site is loading, or when you hover your mouse over a link.
RAM usage - I saw some people's posts about how Chrome only uses up to 70 MB of RAM after one day's use and whatnot. Well, I had Chrome use up 171 MB of RAM just last night after about 10mins or so. What's more, there is a "Google Chrome Helper" process taking up to 50 MB RAM apparently for each open tab, too. Well, at the end of the day, Chrome is probably still a winner in terms of being less of a resource hog than Safari. We'll see.
Speed - yes, Chrome opens quickly and is also quite fast (obviously faster than Firefox), but it's still not as snappy as Safari, which I immediately noticed after browsing a couple of websites. I also ran a Peacekeeper test on both browsers to prove my point, and yes, chrome scored 3500-something, while safari got almost 3900 points. So Safari is a winner here.
Searching - you can virtually use Chrome's URL bar as Google search so whether you are looking for your bookmarked site or non-bookmarked one, it will be really easy to find it, unlike Safari, where it's difficult to find even your bookmarked sites; unless you search by URL and NOT the name of the bookmark, you won't find it. So Chrome is a definite winner here. Oh, and I like how in Chrome when you click on URL bar above, it will immediately highlight it, unlike Safari where you'd need to click on the favicon on the far left of the URL to highlight the entire URL bar.
Favicons - I like how in Chrome you can have favicons on the bookmarks bar, while in Safari you can't. Also, in Safari every now and then it will occur that certain favicons won't get displayed (despite having Glims), which gets annoying to me. Apparently, just like in Firefox, Chrome won't have a problem with that, except it for some reason won't display favicons under "History" tab; don't know why. One thing I miss in Chrome is also a site's favicon to the left of the URL bar. But still, Chrome wins again.
The buttons - I hate Safari's refresh/stop button on the far right. Chrome keeps everything on the left nice and clean. Chrome wins again.
Tabs - Safari tends to beachball every now and then. If it crashes, it will take down the entire app. Chrome, on the other hand, will only crash the problematic tab. Kudos to Chrome on this one too!
Scrolling - still slightly jerkier in Chrome, so Safari wins on this one.
In short, I think when Chrome is fully compatible with 1Password and I'll be able to use most of the Firefox add-ons on Chrome, I'm pretty darn sure switching to Chrome. I'm willing to take the slight difference in snappiness over usability. Btw, when is it supposedly getting released officially?
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