Harry should rest the first team in the second leg. Spurs still have to play Chelsea, Arsenal, Man City and Liverpool in the EPL and need to make up six points on Chelsea to make next year's CL. It's a tall order.
I'd hate to see that as a neutral, but there's clearly logic in it from a league perspective. Mourinho will resolutely park the bus at White Hart Lane and willingly accept a meaningless 1-0 or 2-0 loss to Spurs. He knows he needs to rest his players too, in order to be ready for their inevitable semifinal loss to Barcelona.