Some additional detail on my related (same ?) issue. I also have a macMini 2012, hooked up through displayPort. Exact video path is: macMini <-> OWC ThunderBay <-> ioGear dP KVM <-> Dell S3219D Monitor. Everything great almost all of the time -- except every 10th to 20th switch via the KVM, the display complains about not receiving any signal and proceeds to go into sleep mode -- and at that time, it will not re-establish a connection until the macMini is restarted.
Interestingly, if I remote into the macMini, everything looks correct, and About this Mac -> Displays still shows the monitor connected. If I then disconnect the display, About this Mac acknowledges this disconnect and the loss of the monitor. If I then reconnect the display, then About this Mac shows the monitor reconnected -- but still doesn't not send any signal to the monitor, and when switched to the macMani, the monitor promptly goes back to sleep.
My read on this is that the macMini sends and receives data over the displayPort cable -- until it doesn't, and from that point moving forward, only receives, but does not write video data to the display over the displayPort cable -- at least until one restarts the macMini.
Based on this behavior, to me at least, this feels like a software/OS problem. I also have a Windows 10 machine hooked through the KVM which has never experienced a problem, and 2 Mac laptops connected via thunderbolt to 2 different OWC docking stations -- which also work correctly 99.9% of the time (very, very occasionally, I need to disconnect/reconnect the thunderbolt cable at the laptop end which always causes the display to again work properly -- i.e. no OS restart required).
Unfortunately, machine restarts can be exceedingly inconvenient -- particularly if I have a lot of windows open, and thus, today, I typically just leverage a remote connection until such time that a reboot becomes convenient. Wish there was a better solution to this problem -- but I have been unable to find it as yet...