Math:
Developer/Company:
Currently:
Development and programming, product design, packaging production, marketing, DVD and packaging production, shipping, paying retailers.
App Store:
Development and programming, graphic design for online store, wireless distribution.
Apple handles the marketing and the App Store broadens market exposure. OS X files that don't open effectively use the App Store recommendations, making it easier for the average Joe to identify files (unlike another certain OS's inability to "Find online").
Cutting out DVD production, product design, package production, shipping, saves the company a lot of money. For arguments sake, let's state 30% of those costs are cut (most likely much more as physical media production/plants/etc cost a great deal). Apple handles the marketing and distribution of the product through the App Store and charges a 30% fee. The company now has broader exposure and increased sales, more than accounting for Apple's 30% take.
The App Store is allowing more consumers access to programs they might not otherwise know. Companies such as Apple have/are lowering the programs costs and are breaking up suites such as Adobe CS5, allowing the purchase of individual applications and not unnecessary apps while facilitating immediate consumer access.
Now that downloading 1-2GB movies isn't a big deal with ISPs (OS X Lion was seeded in less than 15 minutes to developers) it's not a stretch to see where this is going: full digital wireless application distribution.
Someone stated that storing app's on your computer isn't any good if you don't have off-site storage in case of fire or other such disasters. The same would happen with physical media so that point seems moot. As well, Apple has yet to activate their new $2B server farm in N.C. with rumors of off-site media storage, taking that claim out of the equation (there are companies that currently offer off-site storage at acceptable speeds). "Time Machine" is also a great system for saving data and full system restores unlike any commercially available system to date.
There seems to be a lot of picking over semantics and not so much over facts.