I can't say that I use it any differently to my Apple TV 3 but I use it a lot. I use it for watching Netflix, YouTube and Amazon prime. Most importantly I use it to watch content from iTunes (movies and videos). I have a huge library.
I do play games from time to time too. The interface is much better on the new Apple TV and I prefer the Siri Remote to the older remote. So it was worth the upgrade.
Since when is Amazon Prime available on ATV4 or any ATV??? Dont tell me your forced to do that lame work around of streaming it from ipad or iphone.