Nope! Not gonna happen. Here are a few reasons why:
1) No more virtualization of Windows on Mac.
2) No more directly running Windows on Mac (aka Boot Camp).
3) No way Intel is going to license their CISC proprietary technology to Apple to run on A-Series RISC CPUs.
4) Most Mac software would be dead-ended and would have to be substantially rewritten to run on RISC CPUs.
5) No more macOS = UNIX without a major rewrite of UNIX for RISC CPUs.
6) There is at this time no realistic speed advantage for moving from Intel CISC chips to Apple A-Series RISC chips.
7) No more GPUs for Mac without again a substantial driver rewrite, if that's even possible with the loss of proprietary Intel CISC technology. Apple has screwed things up badly for Mac GPUs already, locking out anything new by Nvidia, aka stupid move.
And there's more. But I find the above is enough to freak out most Mac users.
And please, those who don't understand the difference between CISC based Intel CPUs and A-Series RISC based CPUs, please read about the difference before making statements that prove your ignorance. Thank you. Oh and no, Apple's Marzipan project is entirely unrelated to this stupid rumor.
The real Question: Why does this stupid rumor come up year after year? IMHO it's re-perpetrated by those who have no idea of the technology shift involved or the damage that would be done to the Mac market if it happened.