Sounds like a pretty good backup scheme.
I'm still stewing about how to set mine up. No hurry though. However, I'd really like to know if it's better to plug into an eSATA for the OS/Apps drive, allowing all of the drives on the RAID controller to actually run a RAID volume. To me, and this is just my humble opinion, it seems a waste to use up a drive connected to the RAID card but not actually part of a RAID set. YMMV, as I said, I'm just stewing...
Why mess with external SATA connectors, hacking around with the insides of the Mac, when there is little to nothing to gain by doing so. I'm a systems engineer for a server software company, I have worked with server hardware and software for 15 years, I am very comfortable with such things, but it comes down to not wanting to spend my free time tweaking for the sake of tweaking, when there are so many other things to spend my time enjoying my computer with. The RAID construct that I have now is very capable, without going crazy on it. It blows away any machine I've ever owned, and my backup strategy will ensure that my family's digital memories will be safe, and serving them up to the extended family will be a ton of fun with OSX Server. This box also makes a great lab platform for me for virtual machines supporting multiple disparate OS's (FreeBSD,Win2K3 Server,Vista,XP,RedHat, etc.).
Most folks recommend creating a single, fast, dedicated boot drive, for nothing but the OS (or multiple OS's via VM's) and the apps. Search in the forums on macgurus.com under the RAID area. When the subject of RAID'ing your boot drive comes around, most IT professionals will tell you that it is total overkill at best, and a misguided use of resources at worst. Any machine of the power and speed of the current MacPro's is very capable of running complex software at a lightning fast pace...the bottlenecks come up when modifying or reading data, especially large files like HD video, high resolution photography, etc. That is why its so great to leverage a high-speed hardware RAID solution for the Data volume(s). The speed is a huge part of it, and of course the fault tolerance of being able to keep working even when a drive fails. It's a fact that software is much more easily replaced than the cherished memories we all have in our photos, movies, music, etc. Put your RAID emphasis on data files, not software applications. Use daily/weekly backups to provide a DR scheme for your software. Do the same for your data as well, but with the added peace of mind that you've also got some internal failover capability on box (not to mention the speed gains!)....
That's my take on all this, after noodling on it night and day for a week, prior to getting the new toy!
By the way, keep in mind that the single JBOD+ disk for OS/apps still benefits from the 256MB cache on the RAID card, not to mention the backup battery should a power event occur. It's not like you are getting no benefit from the RAID card for that drive. To each his own, for sure...the nice part is that none of this needs to be permanent, if you choose a strategy, and you don't like it, just re-image and start over...trial and error are most likely the best approach.