I'll try to be more clear... but first, take a look at Apple's website. They describe the "spot"
http://www.apple.com/antenna/ very clearly here. The part about the hands... if you look at the first set of comparisons where the left side is practically holding the phone only with fingers while the right side is just holding the phone on the palm of the hand... this is what I'm talking about.
I naturally hold my phone like the picture on the right.... not with my fingers. It was never an issue with any of the previous iPhones. With the iPhone 4, this covers the one vulnerable spot on the phone, which causes issues for me. It's not bad if you pick up the call with your right hand. It's also not bad if you are left handed and navigate the screen with your left. Both of these scenarios will most likely not "touch" the weak spot.
All I'm saying is that I am unlucky enough that I naturally pick up calls with my left hand, therefore touching the spot. I also naturally use my right hand to navigate the phone and therefore touching the spot. I may be in the minority, but that still doesn't mean that there isn't an obvious weak spot on the Phone.
I'm not really arguing the merits of the design. I'm sure most things are a trade-off here and there. I also can't argue whether this issue helps more people than it hurts, as there's no way I can even begin to locate/collect that kind of data besides anecdotal records. I also can't comment on how few are affected because of how many people using cases. What I do know is... when the antenna was internal on the previous iPhones, there wasn't one spot that made the phone extra weak. Sure, the iPhone 4 may have better reception if you don't ever touch that spot... but in my opinion... and because of my usage habits... I'd rather have the old reception capabilities and not have to deal with tip toeing my fingers around the iPhone 4.
Again, Anandtech's article shows that it can be remedied to an extent by insulating the antenna. The kapton tape used was able to almost drop the attenuation by HALF... bringing it nearly to 3GS levels of attenuation when the 3GS is held. If apple can introduce some kind of coating on the frame, something similar might be achieved... making the phone useful to me without a case.