I've had my 6S Plus for a couple of weeks now, first time with the bigger screen and I was skeptical on whether or not it would be too big but I would never go back now. Even with the smaller one I had to use two hands for certain tasks, this is still the case with the plus so it really didn't take any adjustment.
So many people tend to be in denial about that. Once you get near that 5" mark, unless you have piano fingers, it is a two handed operation for some tasks.
Depends on the pockets. I have no problems getting it into my skinny jeans that have longer pockets. It sticks out of the ones that I have with smaller sized pockets.
Same here, had 6 plus since it was launched last year and could never get used to its size. Went with 6s this time and i am much happier aside from battery life.