This is odd, because my co-worker and I have the same monitor, the Asus PB278. I don't have the issue, but he does because he has a dedicated GPU in his machine...
The Problem is still there in the 12.1 Beta.Why do people ever install v*.0 of anything?
I have Windows 10 and it works fine with my 5k monitor at 175% scaling.Lol No it doesn't.
Most users:
"Sierra has been super stable and mostly bug-free, even as a beta for many weeks."
Couple of dolts on Macrumors:
"Sierra breaks EVERYTHING as usual! Apple is doomed!"
Mac OS Sierra seems to have enabled full 4k support to my LG 42UH750V at 60hz with proper scaling over mdp. I could never get it to work properly on el Capitan. So for me Sierra has been a fantastic update scaling wise.
I'm sure that they will fix it in an upcoming release.
I googled that model number and it does not seem to exist.
Download RDM
Some Mac owners are reporting problems with external monitors and the use of scaled resolutions since installing macOS Sierra earlier this week.
Several MacRumors readers using 4K displays have described the disappearance of scaled HiDPI resolutions beyond 1920x1080 since updating from OS X El Capitan, leaving their options reduced to 1080p or a non-scaled native resolution of 3840x2160. Monitors with native 1440p resolutions also seem to have had HiDPI scaling options removed.
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Scaled options in Sierra (left) and OS X El Capitan (right) when holding the Option key.
Owners of larger displays often use Apple's scaled HiDPI resolutions offered in Display preferences to enjoy increased desktop space without reducing the legibility of text. MacRumors forum member Sheza warned:
Some readers have reported unsuccessfully trying alternative monitor cable connections - switching over from DisplayPort to HDMI and vice versa. Others have tried using third-party resolution utilities like SwitchResX, with mixed results.
A separate report posted on StackExchange, viewed 1,259 times, details the same issue:
MacRumors can also confirm that the issue appears to be software-related, since the scaled resolutions reappear when affected Macs are rolled back to OS X El Capitan. The issue does not seem to be limited to a particular monitor brand and the latest Public Beta (10.12.1) of Sierra released on Thursday does not reinstate the missing resolutions.
It's unclear if the change is intentional or whether Apple will re-introduce the scaling options in a forthcoming update. Sierra Beta users are advised to submit feedback to Apple using the Feedback Assistant app located in /Applications/Utilities.
Article Link: Users Report Loss of HiDPI Scaling on External Displays in macOS Sierra