Not likely. Most CD’s, records and cassettes are used and there is a condition rating system so you have an idea about playability and whatnot. Depending on what’s out there you can find mint, never opened media for sale.
Plus there are lots of rare albums and neat stuff as well. Early this year I found a very rare and mostly unknown Tool live album on this website. It was in Russia of all places too. I took a chance and bought it thinking I might receive it, or I might not. But the seller shipped it right away and after a while it arrived. It was in great condition as advertised too.
I rummage around in more than just amazon's third party sellers for used DVDs too, although I've had decent luck there rounding up stuff I had been hunting for. Hand-printed on the packing slip for my purchase of a DVD of a particular performance of Poulenc's Dialogues of the Carmelites was a little note to effect of "Loved this DVD, may it bring you as much joy!" A nice touch, and the DVD was in pristine shape.