Being wise is exercising your wisdom. You can't be wise without wisdom but you can have wisdom and not be wise if you choose not to exercise your wisdom.
I would agree with you that substance abuse blocks the ability to gain wisdom but, I also think that it prevents you from exercising your wisdom. Unless the person is under the substance abuse 24/7, they can and will still gain wisdom.
I think in the end, we will have to agree to disagree about wisdom.
So be it. I think the difference is mostly semantics.