So, briefly, Yes. I have two offices of 24", 22", and 27" cintiq's for my designers, engineers, and architects, have run iPads since day 1 and have joined the staff in using and evaluating every illustration and design app in the App Store. One of our partners lent us an early Pro with a Pencil. They are two entirely different products with entirely different and the only overlap between them is the ability to sketch & paint on screen. If that's your only use for a wacom, then you might as well do it on an iPad Pro. It [will] work well enough for that. ...once the applications get up to speed. Right now it's a handful of raster apps with wildly varying performance. Vector applications for scalable, editable drawings are a ways out yet. On Screen CAD work isn't coming. Parametric 3d modeling isn't coming. etc etc etc. To do all the other things a professional designer does, and do them on an Apple computer, you need OS X and its ability to also run Windows. The downside of a cintiq, if you've never even seen one, is that they weigh a ton and are not meant to be mobile, or even really portable.