I do have a 13" 2016 MBP TB, i7, so it's maxed out, but that shouldn't matter. It works perfectly fast on the laptop as a stand-alone, and this 5K monitor was designed to power and support full video for the new 13"MBP, but once connected to the monitor and close the lid of the MBP, the speed is visibly slower to switch between images, loading images takes a few seconds instead of a second, adjustments sometime don't appear right away, arrowing threw images in full screen is noticeably slower. And it gets even worse after a few minutes, loading an image or fine adjustments take several seconds to appear, very frustrating . If I switch back to the MBP and remove the display then again back to the display, it speeds up, but ultimately slows down again shortly after.
Update: I have since returned the display to Apple and will be receiving a new one on Monday. The scariest part for me was my Time Machine backup drive that kept randomly ejecting on it's own, both in the middle doing something else or was already ejected after waking up from sleep (it never ejected while running a backup). I tried a second external drive for TM and same issue occurred. Wondering if the hub in the monitor may of had issues. I was worried about corrupted backups, so requested a replacement.
If the new display continues with the same issues, I may wait a couple of weeks for either a firmware update or the next MAC OS release before finally dumping it for good, and going back to the Thunderbolt display that wasn't as nice, but issue-free.