I received a new M1 mac-mini a couple of weeks ago. Set up from old iMac, attached hub, display, disks etc. All worked fine until a few days ago when I had first crash. Kernel panic etc. Happened every 15-40mins. After troubleshooting using all the tricks folk have posted on different sites, I found the culprit for me was a bus-powered Rugged LaCie, fire-wire connected drive linked to mac via apropriate dongles to Mac thunderbolt. In particular, it was while the encryption process of the drive was running. Disk was formatted APFS, flexible volumes. I'd used the drive fine, no problem, for a few days before the I started the encryption. I removed that drive and have since kept it well away from the Mac. All has run fine for the last few days. Monitor connected via HDMI, have OWC 4-port hub connected + LaCie d2 Pro + Anker USB-C hub + Logitech webcam. My problem was most definitely linked some how to that particular drive. What was causing it? That I cannot say for sure – I'm no systems analyst. But it was definitely the use of that drive and was coincidental with the encryption - I'd backed-up a pile of stuff unencrypted (using SuperDuper 3.5v3 beta) no problem. Encryption process started - crashes started. Disk removed, no problem. So for me wasn't monitor (I connect HDMI fine), nor the other stuff connected. It was that particular external disk. A confusion for me is that I used the same process on a D2 Quadra disk (same firework dongle set up, back up with SuperDuper, then encrypt) and worked fine. But that is a mains-powered drive, not bus-powered. As I say, I'm no expert so can't say with certainty why it was happening. Maybe some of this will help others, I'm not sure, but for me, isolating the problem to that drive and process helped me get my Mac back. Thanks for others who started this thread. Appreciate it.