got my defender on last night. i also have full ghost armor on the case so it is a very snug fit. i dont recommend that, or at least take off the back portion first so it goes on better.
the case does add some weight. i personally dont have a problem with it. the case is very solid, and im now very confident i can take it anywhere, or throw it in any bag without worry. i also really love the little stand that pops up from the snap on cover. now i dont have to worry about buying a stand for my ipad when i want it to stand up.
for the people wondering if it affects any of the screen....no. it takes up just the area around the screen. so the whole touch portion of the screen is untouched and there are no problems doing anything. surfing, checking email, netflix, and playing some games last night everything was fine. no issues whatsoever.
great case if your looking for maximum protection and have the extra money to spend. im happy i did it, otterbox makes great stuff. the only thing i wish they would have changed (looks like the same issue on the commuter case) is the charging/sync port you have to take off the bottom flap. i wish they would have just put a little plug covering the port so you dont have to take the panel on/off just to charge. it is nice that you can still use the dock if you have one though.