i agree.
dont enable trim. once i disabled trim (from trim enabler app), i havent gotten a single beach ball (i hope i didnt jinx myself!)
i also disable safe sleep mode 3 and set it to regular sleep 0 (ram powered by battery but does not write contents from ram to HD) just to cut back on unecessary read/writes everytime i put the laptop to sleep. probably wont affect long term durability of the drive. just me being paranoid. plus i hardly let my computer go into hibernate mode (usually plugged in always and i always quit my apps before i go into sleep mode or walk away from my computer) plus since the unibody design is in effect, there is never a need to swap batteries during sleep mode!