I have a first gen MBP 17" unibody (early 2009) and it has worked without any problems. (I guess they had a little time to work out the kinks since the 15" came a little bit earlier, in october 2008)
The only thing I never got used to is the terrible soundcard in it, a big difference to both my earlier PowerPC systems and also my later intel systems. It's bearable on maxium sound output, but if you lower the volume you can really hear how the bits gets reduced and there is graininess galore. (I know that this how all digital soundcards work, but different models has different ways to mask it, that's for shure!)
My MBP has something I would love to see on future MBP - an anti-glare screen... One can dream, ok?