I have updated both my iMac 2017 & MacBook Pro 2017, and no issues whatsoever! I have a lot of software installed, but everything made it. Two caveats that may be of assistance to some:
1) SpamSieve will appear to be broken the first time you launch Mail. However, simply re-enable the plugin and it will be good to go. Not sure why it crashes the first time it launches, but after that, it's fine.
2) Unlike SpamSieve, GPGMail (part of the GPGTools suite) actually is INCOMPATIBLE at this time. So, if you use GPGMail to sign PGP messages in Mail, then please wait until an official release by GPGTools.
Other than these two hiccups, it's a great upgrade. TV, Music, Podcasts apps run SO MUCH FASTER than iTunes. For most people, these are going to be fantastic upgrades (the power users may have some troubles until software is updated to the new SDKs).