Yes, it is. Infection is not the only thing vaccines protect against. Effectiveness against hospitalization and death does NOT materially wane, so the implication that vaccines are no good after six months is dangerous.
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Coronavirus (Covid-19) informational thread
- Thread starter yaxomoxay
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It HAS to go to hospitalization rate. If the infections are getting milder, then who cares who catches it.
I'm pretty sure that's why I said in the following sentence. These "vaccines" are more along the lines of therapeutics. Yes, the vaccines prevent serious illness/death.
But wouldn't that apply to every vaccine ever? None of them are 100% effective, nor do they work indefinitely.
The Novavax vaccine may be making its way to the market after many, many delays. It’s a particle subunit vaccine that uses the SARS-CoV2 spike protein to stimulate the immune response. This the mechanism of action found in many other vaccines, like HepB and pertussis. This vaccine should be much more stable than the existing options and not require crazy non-standard refrigeration requirements. That will make for easier distribution in less developed places.
For those who have avoided the vaccine because they don’t trust mRNA or adenovirus viral vector technology, this vaccine could be the answer given it works in a more traditional way. Unfortunately, I suspect a new excuse will come to mind for these people. But maybe it’ll get a few people to change their mind.
For those who have avoided the vaccine because they don’t trust mRNA or adenovirus viral vector technology, this vaccine could be the answer given it works in a more traditional way. Unfortunately, I suspect a new excuse will come to mind for these people. But maybe it’ll get a few people to change their mind.
Polio, MMR, HPV. Imagine for a moment 13yr old girls were being told they need to be injected every 6 mos with gardasil in order to prevent HPV. Sounds more like a therapy for psoriasis than a vaccine.
Well, by definition a therapeutic treats a condition. The vaccines cannot treat an active infection.
I get what you’re saying though. The ultimate effect is similar.
Yes, it’s inconvenient. It’s possible our technology will improve to create a vaccine that lasts more than 6 months. It’s also possible after x number of doses the frequency of boosters may decrease.
There’s a birth control called Nexplanon that lasts 3 years. By comparison it makes the flu shot look inconvenient.
Right, I'm speaking of the effect. The current vaccines do not confer an immunity in any form of the traditional sense. Here is what I am wondering and I know we are not suppose to get political anymore. Why has their been no attempt to sit down with the people who "may or may not know" where this virus came from (potentially a lab)? You'd think maybe we wanna talk to the scientists who made it their life's work of studying coronavirus's at the source and seek some insight? Like, if you were conducting gain of function research, what direction where you going. What were you trying to accomplish, what was the goal? Do you know how to neutralize it?
Over here near the Capitol (Albany) we have three regional hospitals that are all at ICU capacity for the first time. The governor is deploying National Guard troops to assist in understaffed hospitals. We've also recently reopened some state-run vaccine and testing sites.
Correct. So please avoid any further discussion of the politics in this thread, or anywhere outside the Political News forum.
I will reply to particular points in the remainder of your question, but any further discussion of the political aspects is not allowed here.
There have been multiple investigations into the origins of COVID-19, with varying amounts of success, and varying amounts of cooperation from the parties involved.
Here's a summary:
Origin of SARS-CoV-2 - Wikipedia
As with many things on Wikipedia, treat the article as a summary, and if you want details, look at the original cited material.
Here's one of the other results when I searched for keywords: origins of covid-19
Yes, that's why there were investigations. Were they successful in finding a definitive origin? Not especially.
The silent premise here is that there was a leak from a
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There have been investigations into the lab leak hypothesis. There unfortunately there are multiple parties involved, some very powerful, who have an incentive to obscure the truth around GoF research and an accidental release, if that is indeed what happened. I guess I’ll leave it at that so as not to get into politics.
Just because something is being researched doesn’t mean the researchers have a significant understanding of what they’re dealing with. I would assume the (alleged) research being done was focusing more on how viruses evolve and adapt than creating a vaccine or treatment for a specific virus.
That’s the main argument against GoF research, you’re potentially playing with fire.
If the Chinese researchers had information that could prevent or treat COVID, I’m sure the Chinese government would be utilizing it.
The reality is that viruses, unlike most bacteria, are very hard to deal with.
Well, looks like 3 Pfizers gives pretty good protection against Omicron (according to company testing and analysis). I'm just wondering when, if ever, this cycle of mutation, booster, mutation... will ever end.
Unless delta and omicron coinfect a person, then undergo recombination in which the progeny viruses have transmissibility and vaccine evasion of omicron but disease of delta. That would suck.
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Can you elaborate on this comment? The current vaccines for COVID induce neutralizing antibodies via somatic hypermutation and affinity maturation, and they elicit clonal expansion of both CD4+ helper and CD8+ cytotoxic T cells. This is what live, attenuated viral vaccines do.
There has been some discussion about this, including comments from Shi Zhengli, the director of the Wuhan Institute of Virology that has spearheaded bat coronavirus research for nearly two decades. She has stated there were no viruses with similarity to SARS-CoV-2 in her lab and that none of her staff had antibodies to the virus when it first emerged in Wuhan.
But more importantly, we really don't need to examine the WIV because there is already a huge amount of physical evidence that this was, in all likelihood, a spillover event because of the live wet markets in China, including Wuhan where two distinct genotypes were already circulating in the wet markets, one of which was exclusively found in a single wet market, that live animals that are known to be susceptible to SARS-CoV-2 were in these wet markets, including American mink (which died by the thousands on mink farms in Utah) and raccoon dogs, the earliest known human infection was a worker at one of these wet markets, the simple fact that most of these animals were farmed in southern China where more than a hundred (and probably hundreds more in Asia) sarbecoviruses (SARS-related coronaviruses) circulate in bats. The two distinct genotypes alone make a lab leak nearly impossible because it means there must have been two lab leaks at the exact same time and those viruses somehow partitioned themselves in different geographic regions of Wuhan. I'm all for keeping an open mind, but not so open that your brain falls out.
I work on coronaviruses (SARS-CoV-2, MERS-CoV), hantaviruses and influenza viruses. The "lab leak hypothesis" is so unlikely, it's a complete waste of time to even think about. That ship has sailed.
Are the Pfizer and Moderna vaccines live attenuated viral vaccines? Do they prevent transmission?
This will definitely be interesting to see. I can check with the California Dept. of Public Health to see if the data trends higher for vaccinations in the county. I do know that that data can be segmented by vaccinations administered at a hospital versus vaccinations administered at an outside facility. That data may even be basic enough that it may be posted on their site.
BL.
Hopefully I understood their decision correctly! I used to live in the Bay Area (and still have some family there), so I try to keep up on news and stuff like that for the area. But of course now, the data I’m more focused on is the county I live in…and the one the hospital I work at is in.
I suspect it’s also partly due to fatigue. People are tired of hearing about ‘what they should do, what they need to do, follow this, follow that’. It’s mental overload. They can’t handle it. And even though it’s a simple as driving to the one of many locations to take a free booster that also takes less than a minute, should outweigh the inconvenience in trade for protection of your health.
The Education is there, people are just choosing to de-prioritize the next step and mentally block the process.
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CItation please that the booster is anything other than a full dose, as this is directly contrary to what I know about the booster.
In the UK (it might be different in the US) for boosters as opposed to a third dose, my understanding is that the Moderna is given at half a dose and Pfizer at a full dose. It's why there's a difference in classification between boosters and third primaries, as Moderna at half a dose doesn't class as a third primary if you're immunosuppressed.
Moderna doses 1 & 2 are 100 ug, dose 3 is 50 ug.
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Citations are not needed for personal experiences regarding other people's opinions. The other member is not making a statement of fact but rather who he talked too regarding their opinion on the vaccine.