Palm rejection works okay. Regardless, what is the point of more screen if you fully expect to be blocking more of it with your palms? Yeah there are times I'm using the iPad propped up (not in hand), but I still hold it a fair amount too.
Honestly the bezels on my 10.5 are too thin as is. It is actually really hard to use apps/games that make use of dragging things because it's too easy to accidentally drag off the side of the device. The edge of the screen is just too close to the physical edge to utilize dragging. So even less bezel would increase this dead zone of screen real estate. What is the point of more screen if I can't use it properly?
Do you? Most of the time I have my iPad Pro propped up with my cover attached, I’m either drawing, handwriting or typing with mine I’d say most of the time my iPad Pro is not in my hand, even when consuming content it’s either proper up with my case or laying down, I use my AirPods too with it.