Who are the others.
What is the real purpose of the hatch.
What is the Dharma initiative, or better yet,
What is the Hanso Foundation.
What happens if one does not enter the numbers.
Where is Desmond.
Why did the plane go down, or how.
What is it about Locke that allows him to know more.
What is so special about Walt.
What is the significance of the numbers.
Where (or when) is the island.
What really happened to Rousseau and her crew.
Why did the hatch say "QUARANTINE".
Did Rousseau's crew really get 'sick'?
Where did Ethan come from?
Why was he so unbelieveably strong?
What does he want with Claire's baby?
What did the psychic see in Claire's future?
Where did the Polar bears come from?
What is the "defense system"?
Is it associated with the hatch?
What made Locke regain the use of his legs?
WHAT IS THE MEANING OF ALL THIS?????
(P.S. please feel free to add your own questions on.. lets see how many unanswered mysteries there are.)