Yeah, if you wanna fry your motherboard, go ahead, run CS5 off a solid state drive.
Programs like that aren't meant to run on flash storage devices.
A hybrid? Sure. It's an interesting concept, and it's gonna increase battery life, boot time and performance.
But if you're going to run CS5...you need the optical drive to install it and a traditional hard drive.
If they move to 100% SSD, then they will have made the MacBook "Pro" a toy like the Air.
Don't get me wrong-the Air is an awesome machine, but if you're a serious designer running serious design programs, solid state drives won't be the best thing for it. Then again, if you're not a serious designer, and you've got money to throw away...which you will when you replace the hard drive in a few months or a year or so when the silicon crack...by all means, get it.
Of course, if Apple has decided to implement SSD, they will have realized they need to ramp up their cooling system...and maybe it is possible, but as far as I know, they're not reporting rumors of a better cooling system.
If they can solve the heat problem and make it run as quickly and as powerfully as current machines...fine. It'll make a more durable product and I'm all for it. But from everything I know, it would be a mistake for Apple to do that.