NO - not by default. But YES - you can curate a kext to make it work. And, each macOS update breaks it. Luckily the NVMe kext hack has been updated every time macOS has been updated so far. You can't boot from an NVMe blade. BUT…macOS 10.13 may well bring system level support for NVMe (maybe even boot support - who knows?), so you can only use your NVMe blade for data at the moment.