Not really.See lots of you discussing eSIMs, is there a real advantage to using them if you only have and use one SIM?
The only major benefit I can think of is improved security, where the eSIM is tied to the device and can't be migrated to another device without EE's help (iOS does have a feature to migrate eSIMs to another device, though this reportedly does not work with EE).
The security argument is a moot point if you enable the PIN on the physical SIM card, where it needs unlocking every time the phone is rebooted or if the SIM card is used in another device.