i had the same problems with battery drain as many people when i first got my phone. that said, i used it straight out of the box - no full charge, although it was about 80% right out of the box. when using, i'd get about 1-2% drain every 5-10mins. i knew something was up because i wouldn't get 12hrs out of my phone w/ minimal use.
following the tips listed ITT and other sites, i did the following:
- deleted all email accts & cloud
- restored phone, set up as new
- turned off ping & itunes restrictions
- in system services, turned off compass calibration, location based iads, and traffic; left status bar icon on
- all location services are left on
- from notification center, i removed stock widget (that's all)
- went into facebook app settings, turned off all push notifications (there were about 8 or so turned on)
- in icloud, turned off mail, bookmarks, notes, photostream, documents & data. also turned off icloud backup
- mail is set for fetch every 15mins
- between the steps above, i calibrated my battery - running it to power off, then recharging to 100%
since then, i've noticed significantly better battery. right now, i've been on standby for almost 9hrs, almost 2hrs of usage (texts, emails, calls, internet, map), and battery sits at 77%