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Several counties including mine here in Colorado have reinstated a mask mandate beginning Wednesday. The governor wasn't willing to do it so the counties finally did.
 
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The point is its fading away slowly despite only 76% vaccination rate in Japan. Its probably a turning point towards something.
I really doubt it. The mutations that are leading to this appear to be occurring in nsp14, which encodes the exonuclease that is principally involved in proofreading that reduces mutations in coronaviruses (this family of viruses is the only one with proofreading and error correction among RNA viruses, and which allow them to have among the largest genomes of RNA viruses at about 30,000 nucleotides). Mutations that compromise nsp14 are catastrophic for coronaviruses, so even if this variant becomes extinct in Japan, there are plenty of other sources of delta (and others that may emerge) to establish in Japan again.

To me, what's really interesting is that it may provide clues as to how to construct an infectious clone that is attenuated that may be useful as a vaccine candidate.
 
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Well, in classic government timing, US announced international flights would resume just days before the news media reported a new surge in Europe. This virus is not going to fade away. It's getting too much help. (Oh wait, I forgot... it's just going to disappear. Yeah, that sounds better.)
 
I asked my doctor should I get the Moderna booster shot. He replied probably not, but could be advisable by late this year.

My son is getting the Pfizer because of the myocarditis concern. He was going back and forth as the Moderna has better efficacy. I read a paper last night that tried all of the vaccination combinations with boosters and the highest was Moderna, Moderna, Moderna. The highest I could get after Pfizer/Pfizer was a Moderna booster. The weakest combination was J&J + J&J.
 
My son is getting the Pfizer because of the myocarditis concern. He was going back and forth as the Moderna has better efficacy. I read a paper last night that tried all of the vaccination combinations with boosters and the highest was Moderna, Moderna, Moderna. The highest I could get after Pfizer/Pfizer was a Moderna booster. The weakest combination was J&J + J&J.
Do you have a citation/source for said paper?

From my understanding, The majority of all these boosters will increase the individual to about 90%.
 
Moderna Booster this morning. 25 ml. No line and the process was very fast. Doing all of the paperwork online makes the process a lot faster. Appointments are booking into the latter part of the first week in December right now and I expect the queue to get a lot longer as more people book.

I registered my vaccine info at another hospital as the first hospital that I registered at indicates that they are verifying my info. I submitted it a few weeks ago. If your state won't do electronic verification, then hospitals might as well. Our state recently accepted $22 million from the Feds for updating our vaccination site so that may get us State QR codes but it might take a while.
I sure hope you didn't get 25ml, it's actually half the dose of the first 2: 0.25ml ... sorry, couldn't resist to point out that typo :)
When I got mine there were plenty appts available, not so much anymore
 
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I sure hope you didn't get 25ml, it's actually half the dose of the first 2: 0.25ml ... sorry, couldn't resist to point out that typo :)
When I got mine there were plenty appts available, not so much anymore

I read it to quickly.

Screen Shot 2021-11-23 at 4.00.06 PM.png
 
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I had a look at the Schools section of our state COVID portal and it looks like every school in the state is in there. It shows active cases, recovered cases, number of clusters. So that's how COVID is getting spread and why we have record active counts and new cases per day and why our hospitals are overloaded. The Governor is working on the latter problem.
 
48 hours later, and it’s already national news. The latest mutation, out of Africa, ‘Omicron.’


They (Health experts) have already been talking about it regionally in our area, and even though they’re closing flight patterns to Africa, it’s likely already in the U.S.

Our local epidemiologist mentioned the boosters are in perfect timing, but we don’t know how they will fare against some thing that seems ultimately that will be the new game changer over Delta.

Even more concerning than that, is this the perfect storm of the holidays and if this variant is even more dangerous (Assuming it’s managed it’s way in the U.S), what can we expect over the course of the next seven weeks.
 
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48 hours later, and it’s already national news. The latest mutation, out of Africa, ‘Omicron.’


They (Health experts) have already been talking about it regionally in our area, and even though they’re closing flight patterns to Africa, it’s likely already in the U.S.

Our local epidemiologist mentioned the boosters are in perfect timing, but we don’t know how they will fare against some thing that seems ultimately that will be the new game changer over Delta.

Even more concerning than that, is this the perfect storm of the holidays and if this variant is even more dangerous (Assuming it’s managed it’s way in the U.S), what can we expect over the course of the next seven weeks.
Elon take me to Mars
 
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There are roughly 13 flights a week from S. Africa to the USA, so the chances of Omicron NOT being in the USA is pretty much zero. Sounds like the first infections started around November 9th so that is plenty of time. It appears to be much more infectious but no word yet on how sick it makes you.
 
There's a big crush for Americans to return to the US before flights are banned so yeah, chances of it not getting here are zero. It will be interesting to see how fast it spreads. There's one report from a female doctor saying that all of the cases that she's seen have been mild. There's a report from another doctor who works in the ICU saying that the cases are moderate to severe. We need a lot more information on how dangerous this is and how it affects the vaccinated and the unvaccinated. If you thought it was hard to hide from Delta, this is Delta on steroids.
 
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There's a big crush for Americans to return to the US before flights are banned so yeah, chances of it not getting here are zero. It will be interesting to see how fast is spreads. There's one report from a female doctor saying that all of the cases that she's seen have been mild. There's a report from another doctor who works in the ICU saying that the cases are moderate to severe. We need a lot more information on how dangerous this is and how it affects the vaccinated and the unvaccinated. If you thought it was hard to hide from Delta, this is Delta on steroids.
I agree. We need more info before it is clear this presents a greater threat than the delta variant. Get vaccinated. Get boosted. Don't freak out.
 
Chances are omicron here and has been here, it’s only a matter of time before the monitoring system in place picks it up. If it’s in Europe and Canada, which it is, it’s going to pop up here. Restricting travel is only going to slow the spread.

Unfortunately there’s very little info on what we should be expecting here. South Africa claims cases are mild, but it’s still early in the game and given their outrage over travel restrictions I think there should be some scrutiny as to whether they are trying to downplay the severity for political/economic purposes.

I think it’s highly unlikely the virus will be completely resistant to the current vaccines. But we need to be doing to more to ensure all of Africa has access to vaccinations, otherwise variants will continue to arise. The new antiviral therapeutics look promising, however the typical issue with antivirals is that they are extremely time sensitive- usually having to be started within a couple days of symptom onset to be effective.
 
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There are two Welsh rugby teams out in SA. Well, one now. One has had to isolate in SA due to positive tests (one with Omicron) but they were trying to get back before the UK red listed the country. The other team are isolating in a hotel in the UK.

A good few hundred passengers have been stuck in Amsterdam on flights from SA (a hub airport for many destinations including SA). Many have tested positive. Dutch reckon in that number are a few with the new strain.

Already popped up in the UK. Don't forget people are savvy and circuitous routes are a thing.
 
What we don't know:
If the new variant is more transmissible than the delta variant
If the new variant is more sever or deadly than the delta variant
If the new variant is able to evade vaccines

Right now, out of an abundance of caution, governments are assuming the worst. News agencies are also assuming the worst because, well......that's what they do. But, the truth is that we just don't know. Ironically, there exists a scenario that is actually a big win in fighting this virus. A less sever virus that is more transmissible could replace the delta variant with one much less consequential to public health. Again, we don't know at this point, but there could be silver lining. We just need to be patient and let science do its work.
 
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