USB isn't the fastest thing in the world. Probably fast enough, but I would think Apple would more likely use one of the SATA ports instead. Which brings up SATA flaw discussions, of course.
If it's read-only, so you can only put OSX on it, that would mean effectively wasted space which could be used to put apps on. I don't think that's a very Apple thing to do.
My money is on a simple DVD replacement, where speed isn't an issue. In that scenario, Apple might not care about non-Apple software. They would just want a small cheap, low-performance memory chip.
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